Question on Block Storage Snapshots utility

Hi,

I'm going to automate a daily snapshot of all my volumes. Some of them are attached to an instance and some others not.

When you do a manual snapshot of a volume that is attached to an instance, a warning popups saying that it is better to detatch the volume before to avoid integrity data loss.

My question is, Can I develop a script to automate the snapshots of all my volumes without worring about "breking" the volume itself? Besides the warning regarding the integrity of the data, is there any other thing I should concern about?

Thanks!